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WebMar 1, 2007 · Transient alkalization caused by activation of the BK(Ca) channels has been reported to be essential for the activation of proteolytic enzymes and bacterial killing in the leukocytic phagosomes. We investigated the effects of high glucose concentrations on these processes in THP-1 cells. WebMar 4, 2024 · The THP-1 human monocytic leukemia cell line is a useful model of macrophage differentiation. Patch clamp methods were used to identify five types of ion channels in undifferentiated THP-1 monocytes. (i) Delayed rectifier K+ current, I DR, was activated by depolarization to potentials positive to −50 mV, inactivated with a time … dark red shoe polish scuff coverWebDec 13, 2024 · Purpose BK Polyomavirus (BKPyV) infection manifests as renal inflammation and can cause kidney damage. Tumor necrosis factor-α (TNF-α) is increased in renal inflammation and injury. The aim of this study was to investigate the effect of TNF-α blockade on BKPyV infection. Methods Urine specimens from 22 patients with BKPyV … dark red scarf men

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