WebDagla tm1a(EUCOMM)Wtsi: Name: diacylglycerol lipase, alpha; targeted mutation 1a, Wellcome Trust Sanger Institute: MGI ID: MGI:4432581: Gene: Dagla Location: Chr19:10222629-10282241 bp, - strand Genetic Position: Chr19, 6.55 cM Alliance: Dagla tm1a(EUCOMM)Wtsi page IMPC: Dagla gene page WebThe gene view histogram is a graphical view of mutations across DAGLA. These mutations are displayed at the amino acid level across the full length of the gene by default. …
Rare genetic variants in the endocannabinoid system genes
WebCatalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development … WebJan 30, 2024 · There were 349 target genes in total. Among them, DAGLA is a lipid metabolic gene. The 3′ UTR site of it was predicted to interact stably with miR-223, and … how to check your b12
Dagla MGI Mouse Gene Detail - MGI:2677061 - diacylglycerol …
WebOrder. Sequence variants and/or copy number variants (deletions/duplications) within the DAGLA gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported. Benign and likely benign variants are generally not reported. Reflex to clinical exome ("All-in-One ... WebJun 17, 2024 · DAGLB is a gene duplication of DAGLA 24. Although DAGLA is the dominant 2-AG synthase in most neurons and accounts for 80% of 2-AG production in the CNS 22, 23, our gene expression and functional assays demonstrate that DAGLB mediates the major 2-AG biosynthesis in nigral DANs. WebMay 1, 2024 · Among the three SNPs in the DAGLA gene, rs879486 did not show association with alcoholism in the Japanese subjects of this study; therefore, it was excluded from further association analysis. On the other hand, because possible associations in the screening were observed for the other two polymorphisms (rs9735635 and … how to check your audio card