WitrynaBuy Immethridine MDA97603 87976-03-2 online for pharmaceutical testing. High-quality reference standards for accurate results. WitrynaIMMETHRIDINE F8ZT2IBM1X Other Structure General Activity Names 3: Identifiers 4: Related Substances 1: IMMETHRIDINE F8ZT2IBM1X Other Details Stereochemistry: ACHIRAL Molecular Formula: C9H9N3: Molecular Weight: 159.1882: Optical Activity: NONE Defined Stereocenters: 0 / 0: E/Z Centers: 0 ...
Histamine receptor agonist alleviates severe cardiorenal damages …
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Immethridine dihydrobromide CAS:699020-93-4 High Purity …
WitrynaImmethridine is a potent histamine H3 receptor agonist (Ki = 0.85 nM). It is selective for histamine H3 over histamine H4 receptors (Ki = 245 nM). Immethridine inhibits cAMP-stimulated β-galactosidase transcription in SK-N-MC cells expressing human H3 receptors (EC50 = 0.18 nM) and induces a concentration-dependent decrease of the … Witryna15 maj 2024 · For example, in animal models of Experimental Autoimmune Encephalomyelitis (EAE) the H3R agonist immethridine decreased the percentage of Th1 and Th17 in the spleen and down-regulated surface molecules (such as CD40, CD86 or MHCII on DCs). R. The regulation of the Blood-Brain Barrier (BBB) by H3R … WitrynaPredicted data is generated using the US Environmental Protection Agency s EPISuite™. Log Octanol-Water Partition Coef (SRC): Log Kow (KOWWIN v1.67 estimate) = 1.13 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42): Boiling Pt (deg C): 363.95 (Adapted Stein & Brown method) Melting Pt (deg C): 121.29 (Mean or … diagnose \\u0026 fix in the hp smart app